The genetic and molecular basis of idiopathic hypogonadotropic hypogonadism
نویسندگان
چکیده
منابع مشابه
Reversal of idiopathic hypogonadotropic hypogonadism.
BACKGROUND Idiopathic hypogonadotropic hypogonadism, which may be associated with anosmia (the Kallmann syndrome) or with a normal sense of smell, is a treatable form of male infertility caused by a congenital defect in the secretion or action of gonadotropin-releasing hormone (GnRH). Patients have absent or incomplete sexual maturation by the age of 18. Idiopathic hypogonadotropic hypogonadism...
متن کاملA Shared Genetic Basis for Self-Limited Delayed Puberty and Idiopathic Hypogonadotropic Hypogonadism
.................................................................................................................................. 4 GLOSSARY OF ABBREVIATIONS AND GENE NAMES .................................................... 6
متن کاملA shared genetic basis for self-limited delayed puberty and idiopathic hypogonadotropic hypogonadism.
CONTEXT Delayed puberty (DP) is a common issue and, in the absence of an underlying condition, is typically self limited. Alhough DP seems to be heritable, no specific genetic cause for DP has yet been reported. In contrast, many genetic causes have been found for idiopathic hypogonadotropic hypogonadism (IHH), a rare disorder characterized by absent or stalled pubertal development. OBJECTIVE...
متن کاملA Shared Genetic Basis for Self-Limited Delayed Puberty and Idiopathic Hypogonadotropic Hypogonadism
.................................................................................................................................. 4 GLOSSARY OF ABBREVIATIONS AND GENE NAMES .................................................... 6
متن کاملGonadotropins in Infertile Men with Idiopathic Hypogonadotropic Hypogonadism
Background Stimulatory therapy with gonadotrpins is an effective treatment to induce spermatogenesis in men with idiopathic hypogonadotroptic hypogonadism (IHH). The aim of this study was to assess the effectiveness of human chorionic gonadotropin / human menopausal gonadotropin on hypogonadotropic infertile men. MaterialsAndMethods This study included fifty-six azoospermic infertile men with I...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2009
ISSN: 1759-5029,1759-5037
DOI: 10.1038/nrendo.2009.177